Sperm Selection

BAIBYSTM

Because we select with care

Cost-saving, fast, fully autonomous, objective, and accurate

  • Complete solution – BAIBYS' system is a complete and integrated solution for autonomous sperm selection
  • Time saving – Fully autonomous procedure at high magnification in minutes
  • Low cost – Reduced costs by saving hours of work by highly qualified embryologists
  • Increasing lab throughput – By shortening procedures’ overall time
  • Fully autonomous – Objective technique, independent of human limitations e.g. subjective interpretation, fatigue, or distraction
  • State-of-the-art technology – AI and robotic-based revolutionary product
  • Latest development – The newest and most innovative high-tech device for IVF centers that routinely perform ICSI
  • Achieves the ultimate goal – Higher pregnancy rates while reducing birth defects
Classic IVF

Classic IVF

Sperm cells compete to fertilize the egg – Natural selection

Normal birth defects
Low success rate
In ~80% of current IVF –

In ~80% of current IVF –

Random sperm cell is injected into the egg (ICSI) to ensure penetration

Higher birth defects
Moderate success rate

Sperm Selection at High Magnification –

Detailed evaluation of sperm cell morphology and motility

Normal birth defects
Higher success rate

Why Select Best Sperm for IVF?

Higher fertilization rate

Sperm quality is a critical factor for embryo development to blastocyst stage

Higher pregnancy and birth rates

Decrease birth defects

The spermatozoon delivers a novel epigenetic signature to the egg (Miller et al, 2010)

What Does Science Say About Sperm Selection?

Conclusions: IMSI (a method of sperm selection at high magnification) seems to be an effective tool at reducing the incidence of structural defects compared to ICSI…

Itoi et al, 2021 >>

The incidence of birth defects was statistically different, with 2.5% (32/1280) in IMSI and 4.5% (119/2627) in ICSI. The results demonstrated that IMSI decreased the incidence of structural defects compared to ICSI – 2.2% (18/830) vs. 3.8% (78/2049) – in a statistically significant manner.

Dieamant et al, 2021 >>

We found a significant differential DNA methylation and expression of many genes in sperm with poor and good morphology.

Cassuto et al, 2021 >>

Tremendous opportunities exist for machine learning to advance male fertility treatments. The fundamental challenge of sperm selection — selecting the most promising candidate from 100,000,000 gametes — presents a challenge that is uniquely well-suited to the high-throughput capabilities of machine learning algorithms paired with modern data processing capabilities.

You et al, 2021 >>

This study demonstrates the value of analyzing sperm morphology using the criteria recommended in terms of predicting fertilization and perhaps pregnancy outcome… If the morphology is not evaluated with care, a diagnosis of unexplained infertility can be made incorrectly and lead to much frustration for both the patient and the physician.

Kruger et al, 1987 >>

Results According to Injected Sperm

Results According to Injected Sperm

The benefit of high magnification

High magnification shows morphological defects, which correlate with low success rate and birth defects.

Standard magnification

At standard magnification no morphological details can be shown.

High magnification

At high magnification morphological defects are clearly shown. Avoiding cells with such defects leads to higher IVF success rate & lower birth defects.

High magnification shows morphological defects